If your Enchantment skill isn’t high the dragon priest mask Krosis offers a 20% bonus to created potions, making it one of the best alchemy items in Skyrim. To make the best potions, you should put as many ranks as possible in the relevant Perks, increase the Alchemy skill, and if you can create a set of gear which boosts Alchemy as much as possible. That formula takes the base ingredient effects and multiplies it by a number determined by a variety of effects the player’s rank in the Alchemy skill, their Alchemist, Benefactor, Physician, and Poisoner Perk bonuses, the enchantments on any items they are wearing, and then any miscellaneous bonuses. When a player creates a potion, the effects of the potion are determined by a particular complex formula. If you don’t want to rely on a glitch, then vendors typically take 48 hours to restock normally. If you buy from a merchant, save the game, then kill that merchant and reload the save their inventory and gold will be restocked. Unfortunately, the easiest way to acquire ingredients in Skyrim is actually based on a glitch.
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